CENTER FOR NEUROSCIENCE IMAGING RESEARCH

Detail

High-resolution fMRI Lab

Introduction

My lab is developing acquisition and analysis methods for high-resolution fMRI in humans. In particular, we are trying to image mesoscopic human brain function using MRI at 7 Tesla. To that end, novel fMRI sequences are developed and tested, analysis pipeline developed, and physiological model of ascending vein effects are applied to the data to remove spatial bias in the fMRI signal. In addition, we are interested in quantitative MRI approaches at 7 Tesla to study subcortical brain organization and cortical brain parcellation in both healthy subjects and patients. Finally, the lab pursues modeling brain connectivity using physiological principles and advanced computational approaches.

Selected Recent Publication

1. J. Polimeni, K. Uludağ. Neuroimaging with Ultra-High Field MRI: Present and Future. NeuroImage 168, 1-532 (http://www.journals.elsevier.com/neuroimage/call-for-papers/neuroimaging-with-ultra-high-field-mri-present-and-future/, 2018, Publisher: Elsevier).

2. K. Uludağ, K. Ugurbil, L. Berliner. Functional MRI: From Nuclear Spins to Brain Function. (http://www.springer.com/gp/book/9781489975904, 2015, Publisher: Springer).

3. I. Marquardt, M. Schneider, O.F. Gulban, D. Ivanov, K. Uludağ. Cortical depth profiles of luminance contrast responses in human V1 and V2 using 7 T fMRI. Human Brain Mapping 39, 2812-27 (2018).

4. S. Kashyap, D. Ivanov, M. Havlicek, B. A. Poser, K. Uludağ. Impact of acquisition and analysis strategies on cortical depth-dependent fMRI. NeuroImage 168, 332-344 (2018).

5. K. Uludağ, P. Blinder. Linking brain vascular physiology to hemodynamic response in ultra-high field MRI. NeuroImage 168, 279-295 (2018).

6. M. Havlicek, A. Roebroeck, K. J. Friston, A. Gardumi, D. Ivanov, K. Uludağ. Physiologically informed dynamic causal models for fMRI. NeuroImage 122, 355-372 (2015).