Friedhelm Christoph Hummel, Ph.D.
November 7(Tue) - November 7(Tue), 2023
3:30 p.m.
86314 & ZOOM
CNIR Seminar
Date: 3:30 p.m., Tuesday, November 7th
https://us02web.zoom.us/j/7281426028
회의 ID: 728 142 6028 (password: cnir)
Speaker: Friedhelm Christoph Hummel, Ph.D.(Swiss Federal Institute of Technology Lausanne (EPFL))
Title: Non-invasive deep brain stimulation: novel opportunities to enhance cognitive functions
Abstract: Deep brain structures such as the striatum, thalamus or hippocampus are core brain areas critically involved in various cognitive functions and the pathophysiology of or recovery from neurological and psychiatry disorders such as Parkinson’s, Alzheimer’s, addiction, stroke and others. Therefore, being able to neuromodulate these structures in-vivo, in humans in a non-invasive way with good topographic resolution would provide a major step forward to better determine the functional role of these structures in healthy and pathological situations in humans and would open a novel way for interventional strategies to treat neurological and psychiatric disorders. Transcranial temporal interference electric stimulation (tTIS) has been proposed as a novel non-invasive brain stimulation technique able to reach deep brain regions without engaging overlaying cortical areas. This method opens novel opportunities to better understand the complex interplay between cortical and subcortical regions involved in motor and cognitive functions. tTIS will be introduced, the mechanistic background examined and first applications to target deep structures in vivo in humans presented (e.g. Wessel, Beanato et al. 2023 Nat Neurosci) and discussed with an outlook focussed on its potential for technological development and clinical translation.