Neurophotonics Lab
Introduction
We use light as a tool to understand and manipulate living biological system, aiming to address pressing problems in neuroscience. Our research theme includes but is not limited to intravital imaging techniques, optical neuromodulation, and bio-integrated photonics. We take multidisciplinary approaches integrating optics, engineering, and biomedicine.
Selected Recent Publications
1. Choi M, Choi JW, Kim S, Nizamoglu S, Hahn SK, Yun SH, "Light-guiding hydrogels for cell-based sensing and optogenetic synthesis in vivo", Nature Photonics 7(12): 987-994, 2013 (featured in Nature Photonics, Nature Methods, Nature Review of Endocrinology, Thomson Reuter, etc.).
2. Choi M, Ku T, Chung K, Yoon J, Choi C, "Minimally invasive molecular delivery into the brain using optical modulation of vascular permeability", PNAS 108(22): 9256-9261, 2011.
3. Kim JK*, Lee WM*, Kim P*, Choi M*, Jung K, Kim S, Yun SH, "Fabrication and operation of GRIN probes for in vivo fluorescence cellular imaging of internal organs in small animals", Nature Protocols 7: 1456-1469, 2012 (*co-first author; cover article).
4. Choi M, Humar M, Kim S, Yun SH, "Step-index optical fiber made of biocompatible hydrogels", Advanced Materials 27: 4081-4086, 2015.
5. Choi M, Lee WM, Yun SH, "Intravital microscopic interrogation of peripheral taste sensation", Scientific Reports 5: 8661, 2015.
Lab Name: Visual Cognitive Neuroscience Lab
Introduction
Visual Cognitive Neuroscience Lab @ SKKU is a research lab investigating psychological and brain processes involved in perception, memory and cognitive control by measuring eye movements and EEGs with solid psychophysics. Currently, we study dynamics of perceptual bistability, contextual memory retrieval, and motor inhibition.
Selected Recent Publications
1. Kang, M.-S., & Choi, J, "Retrieval-induced inhibition in short-term memory", Psychological Science, 26(7): 1014-1025, 2015.
2. Kang, M.-S., Hong, S. W., Blake, R., & Woodman, G.F, "Visual working memory contaminates perception", Psychonomic Bulletin & Review 18: 860-869, 2011.
3. Kang, M.-S., Blake, R., & Woodman, G.F, "Semantic analysis does not occur in the absence of awareness induced by interocular suppression", Journal of Neuroscience 31: 13535-13545, 2011.
4. Kang, M.-S., & Blake, R, "What causes alternations in dominance during binocular rivalry?"
, Attention, Perception & Psychophysics 72(1): 179-186, 2010.
5. Kang, M.-S., "Size matters: A study of the binocular rivalry dynamics", Journal of Vision 9(1): 17, 1-17, 2009.
Nature-inspired Biomateria Lab
Introduction
Our main research scope is to design nature-inspired adhesive materials via catechol or gallol redox chemistry, potential application of which is cardiovascular and neural system. In detail, we have focused on developing a variety of adhesive biomedical formulations (i.e., hydrogels, particulates) exhibiting neuron repair, hemostatic effect, minimally invasive, hemostatic medical devices, adhesion/affinity-based drug-delivery carriers as well as 3D printable inks based on mussel-inspired catechol/its derivatives chemistry for wet-resistant adhesion. The ultimate goal of our research is to design a new generation of biomaterial-based practical medical tools capable of diagnosing and treating actual patients.
Selected Recent Publications
1. Mikyung Shin et al. Nature Materials 2017, 16,147-152
HumAN Lab (Human Affective Neuroscience Laboratory)
Introduction
The overarching goal of our research is to understand the psychological and neurobiological mechanisms that underpin how we experience our own emotions and evaluate the emotions of others. Our lab examines how different aspects of affective information are encoded, manipulated, and integrated in the brain. We also investigate individual differences in such processes on both behavioral and neural levels, and their implications for mental health. We combine experimental psychology, multimodal neuroimaging (fMRI, dMRI), and computational tools to answer research questions pertaining to affective science.
Selected Recent Publications
1. Kim, M. J., Mattek, A. M., & Shin, J. (2020). Amygdalostriatal coupling underpins positive but not negative coloring of ambiguous affect. Cognitive, Affective, and Behavioral Neuroscience, 20, 949-960.
2. Kim, M. J., Farber, M. J., Knodt, A. R., & Hariri, A. R. (2019). Corticolimbic circuit structure moderates an association between early life stress and later trait anxiety. Neuroimage: Clinical, 24, 102050.
3. Kim, M. J., Mattek, A. M., Bennett, R. H., Solomon, K. M., Shin, J., & Whalen, P.J. (2017). Human amygdala tracks a feature-based valence signal embedded within the facial expression of surprise. Journal of Neuroscience, 37, 9510-9518.
4. Kim, M. J., Shin, J., Taylor, J. M., Mattek, A. M., Chavez, S. J., & Whalen, P. J. (2017). Intolerance of uncertainty predicts increased striatal volume. Emotion, 17, 895-899.
5. Kim, M. J., Gee, D. G., Loucks, R. A., Davis, F. C., & Whalen, P. J. (2011). Anxiety dissociates dorsal and ventral medial prefrontal cortex functional connectivity with the amygdala at rest. Cerebral Cortex, 21, 1667-1673.
6. Kim, M. J., & Whalen, P. J. (2009). The structural integrity of an amygdala-prefrontal pathway predicts trait anxiety. Journal of Neuroscience, 29, 11614-11618.